Why pushing sensitivity of assays
Normal assays for biomolecules have detection thresholds of around \(pM\). However, a tumor of \(1mm^3\) contains around 1 million cells. Each secrete around 5000 proteins, and the human body has around 5 liters of blood. This gives around \(10^6 \frac{\textrm{prot}}{ml}\), or \(2\cdot10^{-15}\)M
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